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   Maternal Vitamin D Status and Children’S Asthma Or Wheezing: A Narrative Review Article  
   
نویسنده Nazari Zeinab ,Ghaffari Javad ,Dabaghzadeh Abbas ,Ghaffari Negar ,Ranjbar Ali Reza
منبع Journal Of Pediatrics Review - 2021 - دوره : 9 - شماره : 1 - صفحه:1 -8
چکیده    Context: asthma is a chronic inflammatory respiratory disorder, and nutritional conditions affect allergic diseases such as asthma. this study aims to find the relationship between maternal gestational vitamin d levels and asthma progression and wheezing in children later in life. objectives: allergic disorders are common everywhere in the world. asthma is the most chronic inflammatory respiratory disorder among children. it causes significant morbidity and mortality in children as well as adults. vitamin d deficiency or insufficiency, is a global problem. vitamin d has immunological effects, and it may prevent autoimmune diseases. maternal plasma vitamin d during pregnancy has a different impact on children rsquo;s allergic disorders.evidence acquisition: this is a review article. we searched databases, including google scholar, pubmed, sid, irandoc, scopus, until now. the keywords for the search included maternal vitamin d, asthma, wheezing, children, and pediatric. we searched in the mentioned databases until march 2020. fulltext articles in the english language were included in this study. results: a few articles were found in our search. all of them were cohort studies. they evaluated maternal vitamin d and its outcomes in their children rsquous asthma and wheezing using questionnaire data and serum samples. after assessing the articles (more than 100), 15 papers were included in our review. six and four articles showed that higher maternal vitamin d levels reduce children rsquo;s asthma and or wheezing, respectively. in contrast, 7 articles showed no association between maternal vitamin d and children rsquo;s asthma or wheezing. vitamin d does not have any serious side effects. because the articles were heterogenic, a metaanalysis could not be done. conclusions: administering vitamin d supplements or food enriched vitamin d during pregnancy has different effects on the prevalence of wheezing and or asthma in children.
کلیدواژه Asthma ,Children ,Vitamin D ,Pregnancy ,Wheezing
آدرس Mazandaran University Of Medical Sciences, School Of Medicine, Department Of Gynecology, Iran, Mazandaran University Of Medical Sciences, Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Iran, Mazandaran University Of Medical Sciences, Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Iran, Mazandaran University Of Medical Sciences, Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Iran, Institute Of Interventional Allergology And Immunology, Germany
پست الکترونیکی ranjbar@iiai.de
 
 

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