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Shallominthe Active Antimicrobial Constituent of Persian Shallot in Treatment of Oral Herpes: A Double-Blind Randomized Clinical Trial
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نویسنده
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Pipelzadeh Mohammad Hassan ,Amin Mansour ,Shiravi Khozani Abolfazl ,Radmanesh Mohammad
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منبع
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Jundishapur Journal Of Natural Pharmaceutical Products - 2014 - دوره : 9 - شماره : 3 - صفحه:1 -4
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چکیده
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Background: previous studies showed that shallomin,the active antimicrobial constituent of persian shallot,has a wide range of antibacterial and antifungal properties. objectives: the objective of this randomized clinical trial was to evaluate the effectiveness of topical shallomin alcoholic solution in treatment of cold sore. patients and methods: a total of 60 volunteers who met the inclusion criteria were randomly allocated to two equal groups to hourly apply topical of either 0.5% shallomin alcoholic solution or placebo within the first 24 hours of developing cold sores. all the cases were reassessed at six-hour intervals. results: the cold sores were cleared within six hours among 30% of cases who received shallomin solution and the remaining of the cases in this group were cleared between 6six to 24 hours of application. in the placebo group,clearance of the sores occurred in four cases between 48 to 72 hours and the remaining of cases were cleared after 72 hours. conclusions: the results of this study demonstrated that shallomin is a useful natural remedy in preventing the progression and treatment of cold sores and can significantly reduce the duration of ulceration. © 2014,school of pharmacy,ahvaz jundishapur university of medical sciences.
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کلیدواژه
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Herpes Simples; Cold Sore; Shallomin; Treatment
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آدرس
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Ahvaz Jundishapur University Of Medical Sciences, Toxicology Research Centre, Department Of Pharmacology, ایران, Ahvaz Jundishapur University Of Medical Sciences, Infection And Tropical Diseases Research Center,School Of Medicine, Department Of Microbiology, ایران, Ahvaz Jundishapur University Of Medical Sciences, Infection And Tropical Diseases Research Center,School Of Medicine, Department Of Microbiology, ایران, Ahvaz Jundishapur University Of Medical Sciences, Laser Research Center, Department Of Dermatology, ایران
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Authors
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