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   Ultrasound-Assisted Extraction and Optimization Process Parameters Of Antioxidant and Phenolic Compounds From Myristica Fragrans  
نویسنده Poorhashemi Sahar ,Arianfar Akram ,Mohammadi Ameneh
منبع Jundishapur Journal Of Natural Pharmaceutical Products - 2020 - دوره : 15 - شماره : 1 - صفحه:1 -7
چکیده    Background: ultrasonic extraction is one method for optimization of effective compounds from plants. objectives: the aim of this study was optimization of the extraction conditions of myristica fragrans seeds using ethanol as a food grade solvent and by ultrasonic-assisted extraction using response surface method (rsm). methods: ultrasonic-assisted extraction was used for extraction of m. fragrans seeds. response surface methodology (rsm) was used to optimize three parameters: time and of temperature extraction (min, °c), and solvent to material ratio. antioxidant activity and phenolic contents were determined. results: the results showed that optimal ultrasonic-assisted extraction (uae) conditions were 29.57 minutes extraction time, 374.61 ml/g ratio of solvent to material and 41.89ºc extraction temperatures. the yield of extraction, amount of total phenolic content, ic50 (in dpph method) and frap in m. fragrans seeds in optimum conditions were 18.14%, 63.41 mg gallic acid/g of extract, 43.66 mg/ml and 99.38 mmol/g of extract, respectively. conclusions: the results indicated of the ultrasonic-assisted extraction having power for optimization of the extraction condition and it is appropriate for extraction of antioxidant and phenolic compounds.
کلیدواژه M. Fragrans Seeds ,Ultrasonic-Assisted Extraction ,Response Surface Methodology (Rsm) ,Antioxidant ,Phenolic
آدرس Islamic Azad University, Quchan Branch, Department Of Food Science & Technology, Iran, Islamic Azad University, Quchan Branch, Young Researchers And Elite Club, Iran, North Khorasan University Of Medical Sciences, Natural Products And Medicinal Plants Research Center, Iran
پست الکترونیکی ameneh.mohamadi@yahoo.com

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