>
Fa   |   Ar   |   En
   Lipid rich carcinoma and solid carcinoma in mammary gland of a dog: histopathologic and immunohistochemical features  
   
نویسنده Rezaie Anahita ,Esmaeilzadeh Saleh ,Naddaf Hadi
منبع iranian journal of veterinary science and technology - 2011 - دوره : 3 - شماره : 1 - صفحه:57 -64
چکیده    Lipid rich carcinoma is rare in dog and women and is characterized by cells that have an abundant foamy cytoplasm. A 10 year old, mix breed female dog suffered two subcutaneous masses in ventral abdomen was referred to surgery department of veterinary hospital of Ahvaz Shahid Chamran University. Surgical excision and microscopic examination of masses were done. After grading by Elston and Ellis method, istochemical staining was performed such as PAS, Cong red and Oil Red O.Immunohistochemical detection of pKi67, P53, cerbB2and factor VIII – related antigen were carried out.icroscopically, the masses were two parts; first compose of big cells with vacuolated cytoplasm and euchromatin nuclei andsecond part cells with scant cytoplasm and pleomorphic nuclei and obvious membrane. Grade of tumor was Grade III, poorly differentiated. Positive reaction was seen in vacuolatedcytoplasm for Oil Red O. Neoplastic cells of lipid rich area demonstrated intense immunoreactivity for pKi67. All tumor cells lacked p53 and c-erbB2. This is the first report of coincidence of lipid rich carcinoma and solid carcinoma in a dog with description ofhistopathologic and immunohistochemical characteristics.
کلیدواژه Lipid rich carcinoma ,solid carcinoma ,mammary gland ,P53 ,c-erbB2
آدرس shahid chamran university of ahvaz, 1Departments of Pathobiology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran, ایران, shahid chamran university of ahvaz, Department of Pathobiology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran, ایران, shahid chamran university of ahvaz, Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran, ایران
پست الکترونیکی manager17@um.ac.ir
 
 

Copyright 2015
Islamic World Science Citation Center
All Rights Reserved