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   oropharyngeal candidiasis in children with lymphohematopoietic malignancies in mashhad, iran  
   
نویسنده berenji f ,zabolinejad n ,badiei z ,kakhi s ,andalib aliabadi z ,ganjbakhsh m
منبع current medical mycology - 2015 - دوره : 1 - شماره : 4 - صفحه:33 -36
فایل تمام متن
چکیده    background and purpose: over the past years, the role of fungi as a cause of nosocomial infections in hospitalized patients has been accentuated. candida species constitute an important group of fungi causing diseases in immunocompromised patients. oropharyngeal candidiasis continues to be a prevalent infection in immunodeficient patients. in this study, we aimed to determine the incidence of oropharyngeal candidiasis in children with lymphohematopoietic malignancies. materials and methods: in total, 102 patients with lymphohematopoietic malignancies and 50 healthy controls were examined in terms of candida infections via direct sling of the oropharyngeal cavity. fresh smears were prepared with 10% potassium hydroxide and gram staining was carried out. subsequently, the obtained specimens were cultured on sabouraud dextrose agar for further analysis. results: the most common candida species were candida albicans (31%), other nonc. albicans species (14.7%), c. glabrata (6.8%), and c. krusei (0.98%) in the case group, while in the control group, other non-c. albicans species (10%) and c. albicans (8%) were the most common species. conclusion: in the present study, candida species were the most common fungal pathogens in pediatric cancer patients therefore, efforts should be made to prevent fungemia and fungal pneumonia. also, non-c. albicans species must be considered as a new risk factor for pediatric cancer patients.
کلیدواژه candida species ,lymphohematopoietic malignancies ,oral candidiasis
آدرس mashhad university of medical sciences, school of medicine, iran, mashhad university of medical sciences, school of medicine, iran, mashhad university of medical sciences, school of medicine, iran, mashhad university of medical sciences, school of medicine, iran, mashhad university of medical sciences, school of medicine, iran, mashhad university of medical sciences, school of medicine, iran
پست الکترونیکی m_ganjbakhsh@yahoo.com
 
 

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